Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573750 | 0.94 | LMNA (0.56) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL4574231 | 0.94 | LMNA (0.56) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL106757 | 0.91 | ITGB2 (0.41) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL4894 | 0.82 | — | — | |
| SCHEMBL2886599 | 0.79 | ITGB2 (0.52) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL103524 | 0.71 | — | — | |
| SCHEMBL106035 | 0.71 | — | — | |
| SCHEMBL3417718 | 0.71 | SMN1; SMN2 (0.48) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL2542461 | 0.71 | LMNA (0.34) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3292005 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5869 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141554-A1 | COMPOUNDS AFFECTING KRAS | UNIVERSITAT DE BARCELONA (ES) | 2024-07-04 | — | — | WO | claimed |
| EP-4393908-A1 | BIS-PYRAZOLYL-METHANE COMPOUNDS AFFECTING KRAS | Universitat de Barcelona (ES) | 2024-07-03 | — | — | EP | claimed |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | claimed |
| CN-117820191-A | Diphenylamine compound and preparation method, application and pharmaceutical composition thereof | 复旦大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117683014-A | Thioxanthone photoinitiator containing chalcone structure and preparation and application thereof | 大连理工大学 | 2024-03-12 | — | — | CN | claimed |
| US-11667644-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-06 | — | — | US | claimed |
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | claimed |
| EP-4148053-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | The Global Alliance for TB Drug Development, Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| EP-3426255-B1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT INC (US) | 2022-11-30 | — | — | EP | claimed |
| CN-115322182-A | Azole antifungal compound and application thereof | 广西医科大学 | 2022-11-11 | — | — | CN | claimed |
| US-4399138-A | DIURETICS, ADRENERGIC BLOCKING AND HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-16 | — | — | US | claimed |
| EP-0057572-A1 | Alkanolamine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-11 | — | — | EP | claimed |
| EP-0028355-A1 | 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | claimed |
| US-4221807-A | ADRENERGIC BLOCKING AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-09-09 | — | — | US | claimed |
| US-4140681-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1979-02-20 | — | — | US | claimed |
| US-4131673-A | INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1978-12-26 | — | — | US | claimed |
| US-4125604-A | PEPTIDES, ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4101653-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | claimed |
| US-4093712-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-06 | — | — | US | claimed |
| US-4066773-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-03 | — | — | US | claimed |