SCHEMBL2146209

SCHEMBL2146209

C=CCNC(=O)CNC(=O)C(Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
TSHR P16473 2/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 6/20 0.41
ALDH1A2 O94788 1/20 0.41
ALDH2 P05091 1/20 0.41
ALDH1A3 P47895 1/20 0.41
FAAH O00519 1/20 0.41
HPGD P15428 5/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
HSD17B10 Q99714 2/20 0.39
RAB9A P51151 3/20 0.36
CYP1A2 P05177 1/20 0.34
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10980481 0.86
SCHEMBL17841722 0.74 TSHR (0.60) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL29414586 0.73 ATM (0.42) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL2343053 0.73 TSHR (0.58) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL25635380 0.72 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL1674375 0.72 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL20107210 0.72 TSHR (0.52) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL26091851 0.71 SMN1; SMN2 (0.68) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL7139864 0.71
SCHEMBL880051 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073018-A1 BIODEGRADABLE MICROPARTICLES FOR REDUCING THE VOLATILITY OF BIXOLOZONE FMC CORPORATION (US) 2024-04-04 WO disclosed
EP-4232443-A1 1-(PYRIDYL)-5-AZINYLPYRAZOLE DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH Bayer Aktiengesellschaft (DE) 2023-08-30 EP disclosed
EP-4143181-A1 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH Bayer Aktiengesellschaft (DE) 2023-03-08 EP disclosed
EP-4097087-A1 [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS HERBICIDAL INGREDIENTS Bayer Aktiengesellschaft (DE) 2022-12-07 EP disclosed
WO-2021151976-A1 [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS HERBICIDAL INGREDIENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-08-05 WO disclosed
EP-3599857-A1 HERBICIDAL MIXTURES Bayer Aktiengesellschaft (DE) 2020-02-05 EP disclosed
EP-2755472-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD Bayer Intellectual Property GmbH (DE) 2014-07-23 EP disclosed
EP-2755471-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD Bayer Intellectual Property GmbH (DE) 2014-07-23 EP disclosed
WO-2013037958-A1 USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-21 WO disclosed
WO-2013037955-A1 USE OF ACYLSULFONAMIDES FOR IMPROVING PLANT YIELD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-21 WO disclosed
WO-2011082958-A2 HERBICIDAL AGENTS COMPRISING FLUFENACET BAYER CROPSCIENCE AG (DE) 2011-07-14 WO disclosed
WO-2011082963-A1 HERBICIDAL AGENTS CONTAINING FLUFENACET BAYER CROPSCIENCE AG (DE) 2011-07-14 WO disclosed
WO-2011082956-A2 HERBICIDAL AGENTS CONTAINING FLUFENACET BAYER CROPSCIENCE AG (DE) 2011-07-14 WO disclosed