SCHEMBL1674375

SCHEMBL1674375

C=CCNC(=O)CNC(=O)CN

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.52
TSHR P16473 2/20 0.52
MAPT P10636 2/20 0.52
FAAH O00519 1/20 0.43
ALDH1A1 P00352 5/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 2/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 2/20 0.38
GLA P06280 1/20 0.38
TERT O14746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264763 0.91
SCHEMBL2524054 0.89
Hydrochloric Acid SCHEMBL6029776 0.89
SCHEMBL25658968 0.84 SMN1; SMN2 (0.44) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL22430280 0.81 TERT (0.37) SMN1; SMN2TSHRMAPTTERT
SCHEMBL21664183 0.81 TERT (0.37) SMN1; SMN2TSHRMAPTTERT
SCHEMBL25635380 0.79 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL20107210 0.79 TSHR (0.52) SMN1; SMN2TSHRMAPTFAAHALDH1A1
SCHEMBL7139864 0.78
SCHEMBL17841722 0.78 TSHR (0.60) SMN1; SMN2TSHRMAPTFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3141615-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2019-10-23 EP disclosed
EP-1348713-B1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES INC (US) 2019-01-23 EP disclosed
US-10144956-B2 Processes for quantitative or qualitative detection of single-stranded or double-stranded nucleic acids ENZO BIOCHEM, INC. (US) 2018-12-04 US disclosed
EP-2366798-B1 Nucleic acid detection process involving energy transfer labels on nucleotide ENZO LIFE SCIENCES INC (US) 2017-06-28 EP disclosed
EP-1344835-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2017-06-14 EP disclosed
EP-3141615-A1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS Enzo Life Sciences, Inc. (US) 2017-03-15 EP disclosed
US-9261460-B2 Real-time nucleic acid detection processes and compositions ENZO LIFE SCIENCES, INC. (US) 2016-02-16 US disclosed
US-9068948-B2 Processes for detection of nucleic acids ENZO LIFE SCIENCES, INC. (US) 2015-06-30 US disclosed
US-20130078640-A1 PROCESSES FOR DETECTION OF NUCLEIC ACIDS ENZO LIFE SCIENCES, INC. (US) 2013-03-28 US disclosed
US-8357793-B2 Label target and labeling reagents comprising backbones with at least two consecutive peptide bonds ENZO LIFE SCIENCES, INC. (US) 2013-01-22 US disclosed
US-20060024735-A1 Chimeric nucleic acid constructs and compositions comprising sets of nucleic acid constructs ENZO LIFE SCIENCES, INC. (US) 2006-02-02 US disclosed
US-6949659-B2 Dye labeling composition ENZO LIFE SCIENCES, INC. (US) 2005-09-27 US disclosed
US-20050137388-A1 Real-time nucleic acid detection processes and compositions ENZO LIFE SCIENCES, INC. 2005-06-23 US disclosed
US-20050004350-A1 Novel chemiluminescent reagents ENZO LIFE SCIENCES, INC. (US) 2005-01-06 US disclosed
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes ENZO LIFE SCIENCES, INC. 2004-12-16 US disclosed
US-20040229248-A1 Novel dye labeling composition ENZO LIFE SCIENCES, INC. 2004-11-18 US disclosed
US-20040230036-A1 Heterodimeric dye composition ENZO LIFE SCIENCES, INC. (US) 2004-11-18 US disclosed
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES, INC. 2003-12-04 US disclosed
EP-1348713-A2 Labeling reagents and labeled tabeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses Enzo Life Sciences, Inc. (US) 2003-10-01 EP disclosed
EP-1344835-A2 Real-time nucleic acid detection processes and compositions Enzo Life Sciences, Inc. (US) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229248-A1 Novel dye labeling composition IK, PHAX, CHLSN SMN1; SMN2 4068/4885TSHR 4649/4885MAPT 1877/4885
US-20050004350-A1 Novel chemiluminescent reagents CHLSN, CYBA, HLCS SMN1; SMN2 4691/4885TSHR 3308/4885MAPT 3811/4885
US-20040230036-A1 Heterodimeric dye composition IK, CHLSN, CRY2 SMN1; SMN2 4246/4885TSHR 4498/4885MAPT 2375/4885
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses POLRMT, CHLSN, PHAX SMN1; SMN2 3730/4885TSHR 3683/4885MAPT 2080/4885
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes IK, RBM25, CHLSN SMN1; SMN2 4694/4885TSHR 3063/4885MAPT 2363/4885
US-20050137388-A1 Real-time nucleic acid detection processes and compositions POLRMT, DNTT, RNGTT SMN1; SMN2 2072/4885TSHR 3756/4885MAPT 1437/4885
US-20060024735-A1 Chimeric nucleic acid constructs and compositions comprising sets of nucleic acid constructs DNTT, RNGTT, POLRMT SMN1; SMN2 1539/4885TSHR 3964/4885MAPT 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.