Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27426214 | 0.89 | KDM4E (0.32) | DGAT1 | |
| SCHEMBL31449813 | 0.81 | — | — | |
| SCHEMBL21776649 | 0.79 | NPSR1 (0.34) | — | |
| SCHEMBL4955304 | 0.78 | DGAT1 (0.38) | DGAT1 | |
| Hydrochloric Acid SCHEMBL31191063 | 0.78 | NPSR1 (0.33) | — | |
| SCHEMBL17040615 | 0.76 | — | — | |
| SCHEMBL15055670 | 0.75 | KDM4E (0.35) | DGAT1 | |
| Methane SCHEMBL27653701 | 0.74 | DPP9 (0.30) | — | |
| SCHEMBL30659863 | 0.73 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL24690286 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |