Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.88 |
| ▸ | CA1 | P00915 | 5/20 | 0.88 |
| ▸ | CA2 | P00918 | 5/20 | 0.88 |
| ▸ | CA9 | Q16790 | 5/20 | 0.88 |
| ▸ | CA7 | P43166 | 4/20 | 0.88 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.88 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.61 |
| ▸ | CA6 | P23280 | 4/20 | 0.57 |
| ▸ | CA5A | P35218 | 4/20 | 0.57 |
| ▸ | CA3 | P07451 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,5-Dihydroxybenzoic Acid SCHEMBL618767 | 0.94 | CA12 (1.00) | CA12CA1CA2CA9CA7 | |
| SCHEMBL139644 | 0.94 | CA12 (0.88) | CA12CA1CA2CA9CA7 | |
| 3,5-Dihydroxybenzoic Acid SCHEMBL28106 | 0.94 | CA12 (1.00) | CA12CA1CA2CA9CA7 | |
| 3,5-Dihydroxybenzoic Acid SCHEMBL32679272 | 0.91 | CA12 (0.94) | CA12CA1CA2CA9CA7 | |
| SCHEMBL9178343 | 0.91 | CA12 (0.83) | CA12CA1CA2CA9CA7 | |
| 3,5-Dihydroxybenzoic Acid SCHEMBL1151737 | 0.91 | CA12 (0.94) | CA12CA1CA2CA9CA7 | |
| SCHEMBL31556276 | 0.91 | CA12 (0.83) | CA12CA1CA2CA9CA7 | |
| Methane SCHEMBL6131088 | 0.91 | CA12 (0.83) | CA12CA1CA2CA9CA7 | |
| 3,5-Dihydroxybenzoic Acid SCHEMBL9693437 | 0.91 | CA12 (0.94) | CA12CA1CA2CA9CA7 | |
| SCHEMBL9178351 | 0.91 | CA12 (0.83) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116169425-A | Ionic covalent organic framework functionalized modified diaphragm and preparation and application thereof | 华南理工大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-112952198-B | Sulfur energy storage battery and method for improving rate capability and cycle stability of sulfur energy storage battery | 华中科技大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-112952198-A | Sulfur energy storage battery and method for improving rate capability and cycle stability of sulfur energy storage battery | 华中科技大学 | 2021-06-11 | — | — | CN | disclosed |
| WO-2019199879-A1 | HYDROPHOBIC COATINGS AND METHODS OF MAKING HYDROPHOBIC AND OLEOPHOBIC COATINGS USING ATOMIC OR MOLECULAR DEPOSITION | ALD NANOSOLUTIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |