Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 8/20 | 0.37 |
| ▸ | PI4KA | P42356 | 4/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670853 | 0.83 | PIK3CD (0.47) | NSD3PIK3CDPI4KAPI4K2BPI4K2A | |
| SCHEMBL9009 | 0.83 | PIK3CD (0.47) | NSD3PIK3CDPI4KAPI4K2BPI4K2A | |
| SCHEMBL130916 | 0.72 | ADORA2A (0.48) | PIK3CDPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8577 | 0.72 | ADORA2A (0.53) | PIK3CDPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29651680 | 0.72 | ADORA2A (0.53) | PIK3CDPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8903 | 0.71 | ADORA2A (0.49) | NSD3PIK3CDNSD2PI4KAPI4K2B | |
| SCHEMBL30013159 | 0.71 | ADORA2A (0.49) | NSD3PIK3CDNSD2PI4KAPI4K2B | |
| SCHEMBL19113768 | 0.71 | PIK3CD (0.55) | PIK3CDPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13729010 | 0.70 | NSD2 (0.43) | NSD3PIK3CDNSD2PI4KAPI4K2B | |
| SCHEMBL7930 | 0.70 | ADORA2A (0.48) | NSD3PIK3CDNSD2PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442783-B2 | 2,3-disubstituted chromen-4-one compounds as modulators of protein kinases | PIK3CB, PIK3CD, PDPK1 | NSD3 2598/4885PIK3CD 2/4885NSD2 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.