SCHEMBL214685

SCHEMBL214685

c1nc2n[nH]cc2s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20523348 0.62
SCHEMBL2006685 0.56
SCHEMBL20631802 0.56 PRKD1 (0.34)
SCHEMBL881760 0.55
SCHEMBL1892905 0.55 HSD17B10 (0.34)
SCHEMBL5751246 0.55 ALDH1A1 (0.31)
SCHEMBL1892659 0.55 KDM4E (0.46)
SCHEMBL22230014 0.55 KDM4E (0.39)
SCHEMBL21955971 0.55 ALDH1A1 (0.31)
SCHEMBL21958562 0.55 DAO (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002520-B1 Composition for oxidative dying of keratinous fibres and dying process therewith OREAL (FR) 2008-10-29 EP claimed
WO-2007071686-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
US-7179301-B2 Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group L'OREAL S.A. (FR) 2007-02-20 US claimed
US-6890362-B2 Oxidation dyeing composition for keratinous fibers and dyeing method using same L'OREAL, S.A. (FR) 2005-05-10 US claimed
EP-0988021-B1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME OREAL (FR) 2003-11-12 EP claimed
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-01-16 US claimed
US-6395042-B1 OXIDATION BASE, HETEROCYCLIC COUPLERS FOR OXIDATION COLOR DYE L'ORÉAL (FR) 2002-05-28 US claimed
US-6139589-A HAIR DYES L'OREAL S.A. (FR) 2000-10-31 US claimed
EP-0927021-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-(3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1999-07-07 EP claimed
WO-1998008486-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-[3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1998-03-05 WO claimed
JP-7244361-A None JP disclosed
EP-4580592-A1 HAIR COLORING COMPOSITIONS L'OREAL (FR) 2025-07-09 EP disclosed
WO-2025074120-A1 NANOPARTICLES FOR EXTENDED RELEASE DRUG DELIVERY IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-04-10 WO disclosed
US-12268769-B2 Hair coloring compositions L'OREAL (FR) 2025-04-08 US disclosed
US-12257330-B2 Hair coloring compositions and methods of use L'OREAL (FR) 2025-03-25 US disclosed
CN-1244116-A Oxidising composition and use for dyeing, permanently setting or bleaching keratin fibres OREAL (FR) 2000-02-09 CN disclosed
CN-1243430-A Oxidising composition and uses for dyeing, permanently setting or bleaching kerutin fibres OREAL (FR) 2000-02-02 CN disclosed
EP-0927021-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-(3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1999-07-07 EP disclosed
WO-1998008486-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-[3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1998-03-05 WO disclosed
JP-H07244361-A NOVEL PHOTOGRAPHIC COUPLER AND SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL KONICA CORP 1995-09-19 JP disclosed