SCHEMBL214686

SCHEMBL214686

c1nc2[nH]ncc2s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20523548 0.62
SCHEMBL4404068 0.59
SCHEMBL16714051 0.57
SCHEMBL12907102 0.57 DAO (0.50)
SCHEMBL21480317 0.56 DAO (0.68)
SCHEMBL5751246 0.55 ALDH1A1 (0.31)
SCHEMBL21955971 0.55 ALDH1A1 (0.31)
SCHEMBL22230014 0.55 KDM4E (0.39)
SCHEMBL21958562 0.55 DAO (0.32)
SCHEMBL1892659 0.55 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236135-A1 STABLE PHARMACEUTICAL COMPOSITION Asahi Kasei Pharma Corporation (JP) 2010-10-06 EP claimed
US-20100041725-A1 STABLE PHARMACEUTICAL COMPOSITION ASAHI KASEI PHARMA CORPORATION (JP) 2010-02-18 US claimed
EP-2006271-A9 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2009-07-29 EP claimed
US-20090054401-A1 Substituted bicyclic derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2009-02-26 US claimed
EP-2006271-A2 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2008-12-24 EP claimed
EP-1002520-B1 Composition for oxidative dying of keratinous fibres and dying process therewith OREAL (FR) 2008-10-29 EP claimed
WO-2007071686-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
US-7179301-B2 Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group L'OREAL S.A. (FR) 2007-02-20 US claimed
EP-1660427-A4 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2006-12-20 EP claimed
EP-1660427-A1 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2006-05-31 EP claimed
US-6890362-B2 Oxidation dyeing composition for keratinous fibers and dyeing method using same L'OREAL, S.A. (FR) 2005-05-10 US claimed
WO-2005016862-A1 SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORPORATION (JP) 2005-02-24 WO claimed
EP-0988021-B1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME OREAL (FR) 2003-11-12 EP claimed
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-01-16 US claimed
US-6395042-B1 OXIDATION BASE, HETEROCYCLIC COUPLERS FOR OXIDATION COLOR DYE L'ORÉAL (FR) 2002-05-28 US claimed
US-6139589-A HAIR DYES L'OREAL S.A. (FR) 2000-10-31 US claimed
EP-0927021-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-(3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1999-07-07 EP claimed
WO-1998008486-A2 COMPOSITIONS FOR DYEING KERATIN FIBRES CONTAINING PYRAZOLO-[3,4-D]-THIAZOLES; THEIR USE FOR DYEING AS COUPLERS, DYEING METHOD L'OREAL (FR) 1998-03-05 WO claimed
JP-7244361-A None JP disclosed
JP-H07244361-A NOVEL PHOTOGRAPHIC COUPLER AND SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL KONICA CORP 1995-09-19 JP disclosed