Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21471635 | 0.85 | TPSAB1 (0.40) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL21471633 | 0.81 | HDAC3 (0.34) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL21300881 | 0.78 | TPSAB1 (0.50) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL25666366 | 0.76 | HDAC1 (0.52) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL21470192 | 0.76 | TPSAB1 (0.40) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL21470305 | 0.76 | GAA (0.44) | TPSAB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21470303 | 0.76 | TPSAB1 (0.40) | TPSAB1PRSS1HDAC3HDAC4HDAC1 | |
| SCHEMBL21470304 | 0.73 | HDAC3 (0.39) | TPSAB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21470302 | 0.73 | TPSAB1 (0.38) | TPSAB1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26036186 | 0.73 | TPSAB1 (0.38) | TPSAB1PRSS1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195888-A1 | TARGETING COMPOUNDS AND METHODS FOR THEIR PRODUCTION | THE UNIVERSITY OF MELBOURNE (AU) | 2019-10-17 | — | — | WO | disclosed |