Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.34 |
| ▸ | DRD5 | P21918 | 4/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326727 | 0.89 | HAO1 (0.38) | HAO1HRH3CSF1RAXLMERTK | |
| SCHEMBL21470496 | 0.85 | NR1H2 (0.47) | HAO1 | |
| SCHEMBL21470816 | 0.78 | DRD1 (0.41) | DRD1DRD5HRH3TLR7DRD2 | |
| SCHEMBL21470708 | 0.72 | KIT (0.42) | WNT1GSK3BDYRK1A | |
| SCHEMBL23327006 | 0.70 | F10 (0.39) | — | |
| SCHEMBL21470507 | 0.67 | NR1H2 (0.47) | — | |
| SCHEMBL21470817 | 0.62 | NR1H2 (0.56) | — | |
| SCHEMBL30966834 | 0.62 | GRM5 (0.40) | CSF1RAXL | |
| SCHEMBL30845464 | 0.62 | DRD1 (0.52) | DRD1DRD5HRH3DRD2DRD3 | |
| SCHEMBL10573181 | 0.61 | HRH3 (0.54) | DRD1DRD5HRH3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |