Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.50 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107685 | 0.85 | DHODH (0.51) | DHODHTLR7KDM4E | |
| SCHEMBL21471180 | 0.83 | DHODH (0.52) | DHODH | |
| SCHEMBL20107915 | 0.83 | TLR7 (0.49) | DHODHTLR7KDM4E | |
| SCHEMBL20107888 | 0.80 | DHODH (0.47) | DHODHTLR7NPSR1KDM4E | |
| SCHEMBL23240302 | 0.80 | DHODH (0.52) | DHODH | |
| SCHEMBL23240320 | 0.78 | DHODH (0.57) | DHODHTLR7 | |
| SCHEMBL23240286 | 0.78 | DHODH (0.51) | DHODHTLR7 | |
| SCHEMBL23240323 | 0.78 | DHODH (0.49) | DHODHTLR7 | |
| SCHEMBL23240464 | 0.78 | DHODH (0.50) | DHODHTLR7 | |
| SCHEMBL23240282 | 0.78 | DHODH (0.54) | DHODHTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553052-A1 | 5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL DERIVATIVES FOR THE TREATMENT OF CANCER | Bayer AG (DE) | 2019-10-16 | — | — | EP | disclosed |