Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599068 | 0.88 | NOTUM (0.46) | ALDH1A1KDM4EGAAL3MBTL1CHRM2 | |
| SCHEMBL21471714 | 0.88 | CHRM2 (0.38) | ALDH1A1KDM4EGAAL3MBTL1CHRM2 | |
| SCHEMBL20622402 | 0.88 | HPGD (0.42) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL20619490 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL21471614 | 0.85 | KDM4E (0.36) | ALDH1A1KDM4EGAAL3MBTL1CHRM2 | |
| SCHEMBL21471683 | 0.84 | CHRM2 (0.36) | ALDH1A1KDM4EGAAL3MBTL1CHRM2 | |
| SCHEMBL21471717 | 0.83 | MAPK14 (0.41) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21474620 | 0.83 | MAPK14 (0.41) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21457978 | 0.83 | PIK3CA (0.38) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL21471792 | 0.82 | CHRM2 (0.36) | CHRM2CHRM3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |