SCHEMBL21471753

SCHEMBL21471753

N[C@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 18/20 1.00
MAOA P21397 16/20 1.00
MAOB P27338 13/20 1.00
RCOR1 Q9UKL0 6/20 1.00
KDM1B Q8NB78 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12813993 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL2557921 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL15944933 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B
Hydrochloric Acid SCHEMBL15789127 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B
Hydrochloric Acid SCHEMBL15789125 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL17003579 0.94 MAOA (1.00) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL17003580 0.94 MAOA (1.00) KDM1AMAOAMAOBRCOR1KDM1B
Hydrochloric Acid SCHEMBL17003042 0.92 MAOA (0.97) KDM1AMAOAMAOBRCOR1KDM1B
Hydrochloric Acid SCHEMBL17003041 0.92 MAOA (0.97) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL17287978 0.91 KDM1A (1.00) KDM1AMAOAMAOBRCOR1KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968213-B2 Cyclopropanamine compound and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-06 US disclosed
US-20190315735-A1 CYCLOPROPANAMINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315735-A1 CYCLOPROPANAMINE COMPOUND AND USE THEREOF KDM1A, KDM1B, KDM2A KDM1A 1/4885MAOA 493/4885MAOB 495/4885
US-10968213-B2 Cyclopropanamine compound and use thereof KDM1A, KDM1B, KDM2A KDM1A 1/4885MAOA 493/4885MAOB 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.