⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21472624 | 0.95 | — | — | |
| SCHEMBL21472786 | 0.88 | — | — | |
| SCHEMBL24805499 | 0.86 | — | — | |
| SCHEMBL21472779 | 0.86 | — | — | |
| SCHEMBL21842836 | 0.86 | — | — | |
| SCHEMBL21473453 | 0.84 | — | — | |
| SCHEMBL22649507 | 0.81 | DNM2 (0.36) | — | |
| SCHEMBL22943378 | 0.81 | EPHX1 (0.31) | — | |
| SCHEMBL24806590 | 0.81 | — | — | |
| SCHEMBL21472493 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076805-A1 | MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF | Moderna TX, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| US-20190314291-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS | MODERNATX, INC. | 2019-10-17 | — | — | US | disclosed |