Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411946 | 0.87 | ACACB (0.49) | MAPTALDH1A1ACACBHPGDL3MBTL1 | |
| SCHEMBL16345667 | 0.82 | RARB (0.52) | ALDH1A1ACACBSMN1; SMN2CA1CA2 | |
| SCHEMBL16377529 | 0.80 | CA1 (0.39) | MAPTALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL15960259 | 0.80 | RARB (0.55) | MAPTALDH1A1ACACBHPGDL3MBTL1 | |
| SCHEMBL16340844 | 0.79 | HDAC2 (0.50) | ACACBHPGDKMT2ASMN1; SMN2CA2 | |
| SCHEMBL25834998 | 0.79 | GSK3B (0.44) | ACACBKMT2ASMN1; SMN2GAACA1 | |
| SCHEMBL163209 | 0.79 | ALDH1A1 (0.72) | MAPTALDH1A1HPGDL3MBTL1RAB9A | |
| SCHEMBL6292237 | 0.78 | APP (0.38) | MAPTALDH1A1CA2 | |
| SCHEMBL12285264 | 0.77 | FFAR1 (0.44) | MAPTALDH1A1ACACBHPGDL3MBTL1 | |
| SCHEMBL10001336 | 0.77 | ACACB (0.47) | MAPTALDH1A1ACACBHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210077571-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2021-03-18 | — | — | US | disclosed |
| WO-2019197654-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077571-A1 | TARGETED AMATOXIN CONJUGATE FOR THE TREATMENT OF SOLID TUMORS | C3AR1, ANTXR2, C5AR2 | MAPT 4621/4885ALDH1A1 4043/4885ACACB 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.