Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26190472 | 1.00 | ABL1 (0.47) | ABL1RIN1TMIGD3ADORA3ADORA1 | |
| SCHEMBL22984016 | 0.87 | TYMP (0.46) | TMIGD3ADORA3ADORA1TYMP | |
| SCHEMBL21828786 | 0.87 | TYMP (0.46) | TMIGD3ADORA3ADORA1TYMP | |
| SCHEMBL261967 | 0.87 | TYMP (0.46) | TMIGD3ADORA3ADORA1TYMP | |
| SCHEMBL23056605 | 0.86 | ABL1 (0.65) | ABL1RIN1ADORA3TYMPADORA2A | |
| SCHEMBL21504687 | 0.86 | POLB (0.40) | ABL1RIN1TMIGD3ADORA3ADORA1 | |
| SCHEMBL3070618 | 0.83 | TYMP (0.54) | TYMP | |
| SCHEMBL3070612 | 0.83 | TYMP (0.54) | TYMP | |
| SCHEMBL22983996 | 0.83 | POLB (0.40) | ABL1RIN1TMIGD3ADORA3ADORA1 | |
| SCHEMBL31725429 | 0.83 | TYMP (0.39) | ABL1RIN1TMIGD3ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200273-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-17 | — | — | WO | disclosed |