Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098415 | 0.86 | SPHK1 (0.37) | SPHK1 | |
| SCHEMBL24098481 | 0.83 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL25656599 | 0.83 | — | — | |
| SCHEMBL22605263 | 0.83 | — | — | |
| SCHEMBL25492621 | 0.83 | — | — | |
| SCHEMBL23710650 | 0.83 | — | — | |
| SCHEMBL24135559 | 0.76 | — | — | |
| SCHEMBL23710570 | 0.75 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL23547708 | 0.70 | SPHK1 (0.36) | SPHK1 | |
| SCHEMBL10363402 | 0.70 | SPHK1 (0.36) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995336-B2 | Serpina1 iRNA compositions and methods of use thereof | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-20190316127-A1 | SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF | BANK OF AMERICA, N.A. | 2019-10-17 | — | — | US | disclosed |