Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.95 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.85 |
| ▸ | LDHB | P07195 | 4/20 | 0.43 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.38 |
| ▸ | BECN1 | Q14457 | 7/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474097 | 0.98 | KDM1A (0.99) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL14845813 | 0.98 | KDM1A (0.99) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL29394303 | 0.98 | KDM1A (0.99) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL25641510 | 0.98 | KDM1A (0.99) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL21476977 | 0.97 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL31066574 | 0.97 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL49226 | 0.97 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL18902532 | 0.97 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL21474085 | 0.96 | KDM1A (0.95) | KDM1ARCOR1LDHBTERF2IPF11 | |
| SCHEMBL14845493 | 0.96 | KDM1A (0.95) | KDM1ARCOR1LDHBTERF2IPF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556769-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2019-10-23 | — | — | EP | disclosed |
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CAMS (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | NPEPPS, MYD88, MRPL21 | KDM1A 2143/4885RCOR1 1398/4885LDHB 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.