Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458412 | 0.89 | TSHR (0.43) | MAPTTSHRSMN1; SMN2RECQLPRKCA | |
| SCHEMBL15491409 | 0.89 | TSHR (0.43) | MAPTTSHRSMN1; SMN2RECQLPRKCA | |
| Ethane SCHEMBL2861058 | 0.87 | TSHR (0.42) | MAPTTSHRSMN1; SMN2RECQLPRKCA | |
| SCHEMBL574287 | 0.83 | MAPT (0.44) | MAPTTSHRRECQLPRKCAALDH1A1 | |
| SCHEMBL8954811 | 0.78 | MAPT (0.47) | MAPTTSHRSMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL8954807 | 0.78 | MAPT (0.47) | MAPTTSHRSMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL1172359 | 0.78 | MAPT (0.47) | MAPTTSHRSMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL14672440 | 0.78 | MAPT (0.41) | MAPTTSHRRECQLPRKCATDP1 | |
| SCHEMBL5907693 | 0.77 | MAPT (0.43) | MAPTTSHRRECQLPRKCATDP1 | |
| SCHEMBL18924829 | 0.77 | MAPT (0.46) | MAPTTSHRSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683351-B1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |