Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744311 | 0.86 | MAPT (0.42) | MAPTELANEPRKCATSHRRECQL | |
| SCHEMBL574287 | 0.85 | MAPT (0.44) | MAPTELANEPRKCATSHRRECQL | |
| SCHEMBL14069518 | 0.84 | MAPT (0.41) | MAPTELANEPRKCATSHRRECQL | |
| SCHEMBL14672440 | 0.84 | MAPT (0.41) | MAPTELANEPRKCATSHRRECQL | |
| SCHEMBL5907649 | 0.84 | MAPT (0.44) | MAPTPRKCATSHRRECQLCYP3A4 | |
| SCHEMBL19899199 | 0.83 | MAPT (0.43) | MAPTPRKCATSHRRECQLCYP3A4 | |
| SCHEMBL21775801 | 0.83 | MAPT (0.43) | MAPTPRKCATSHRRECQLCYP3A4 | |
| SCHEMBL21775800 | 0.83 | MAPT (0.43) | MAPTPRKCATSHRRECQLCYP3A4 | |
| SCHEMBL24414507 | 0.82 | MAPT (0.53) | MAPTPRKCATSHRTDP1KDM4E | |
| SCHEMBL24414468 | 0.82 | MAPT (0.53) | MAPTPRKCATSHRTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |