⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosemicarbazide SCHEMBL8825100 | 0.96 | — | — | |
| Thiosemicarbazide SCHEMBL18890136 | 0.96 | — | — | |
| Thiosemicarbazide SCHEMBL28299600 | 0.96 | — | — | |
| Thiosemicarbazide SCHEMBL27681364 | 0.83 | — | — | |
| SCHEMBL11666815 | 0.67 | — | — | |
| SCHEMBL5838983 | 0.67 | — | — | |
| Pimagedine SCHEMBL7763659 | 0.67 | ALDH1A1 (0.43) | — | |
| Pimagedine SCHEMBL15307 | 0.67 | — | — | |
| SCHEMBL1037190 | 0.67 | — | — | |
| Dicarbonodithioimidic Diamide SCHEMBL3077015 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753405-B2 | 1,3,4-thiadiazole compounds and their use in treating cancer | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-09-12 | — | — | US | disclosed |
| EP-4213943-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | The University Of Montana (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022060905-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | THE UNIVERSITY OF MONTANA (US) | 2022-03-24 | — | — | WO | disclosed |
| US-10981904-B2 | 1,3,4-thiadiazole compounds and their use in treating cancer | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2021-04-20 | — | — | US | disclosed |
| EP-3521339-A1 | POLYMER, COMPOSITION, AND MOLDED ARTICLE | Daikin Industries, Ltd. (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-10323028-B2 | 1,3,4-thiadiazole compounds and their use in treating cancer | ASTRAZENECA AB (SE) | 2019-06-18 | — | — | US | disclosed |
| CN-108752322-A | A kind of novel Tepotinib derivatives and preparation method and its application in antitumor drug | 广州新民培林医药科技有限公司 | 2018-11-06 | — | — | CN | disclosed |
| US-20170247688-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2017-08-31 | — | — | US | disclosed |
| EP-2341140-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | disclosed |
| EP-2336315-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | disclosed |
| US-9227971-B2 | Pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-01-05 | — | — | US | disclosed |
| EP-2336147-B1 | A beta immunogenic peptide carrier conjugates and methods of producing same | JANSSEN ALZHEIMER IMMUNOTHERAP (IE) | 2014-04-30 | — | — | EP | disclosed |
| US-20120322791-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME LLC | 2012-12-20 | — | — | US | disclosed |
| US-20120322791-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME LLC | 2012-12-20 | — | — | US | disclosed |
| US-20120322791-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME LLC | 2012-12-20 | — | — | US | disclosed |
| EP-2479184-A2 | Beta immunogenic peptide carrier conjugates and methods of producing the same | Janssen Alzheimer Immunotherapy (IE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2460813-A1 | A beta immunogenic peptide carrier conjugates and methods of producing same | Janssen Alzheimer Immunotherapy (IE) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011090935-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-28 | — | — | WO | disclosed |
| EP-1699810-A2 | A BETA IMMUNOGENIC PEPTIDE CARRIER CONJUGATES AND METHODS OF PRODUCING SAME | Elan Pharmaceuticals, Inc. (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005058941-A2 | Aβ IMMUNOGENIC PEPTIDE CARRIER CONJUGATES AND METHODS OF PRODUCING SAME | ELAN PHARMACEUTICALS, INC. (US) | 2005-06-30 | — | — | WO | disclosed |