SCHEMBL21474925

SCHEMBL21474925

OC1CCc2cc3ccccc3cc2-c2ccc3ccccc3c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
NR3C1 P04150 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6944904 0.79 CYP1A2 (0.51) CYP1A2CYP2C9HIF1ACYP2D6CYP2C19
SCHEMBL24203000 0.78 CYP1A2 (0.38) CYP1A2CYP2C9HIF1ACYP2D6CYP2C19
SCHEMBL6945155 0.69 GFRA3 (0.41) CYP1A2CYP2D6CYP2C19MEN1MAPT
SCHEMBL30585507 0.66 ANPEP (0.41) CYP1A2HIF1ACYP2C19HTTSMN1; SMN2
SCHEMBL1155357 0.66 ANPEP (0.41) CYP1A2HIF1ACYP2C19HTTSMN1; SMN2
SCHEMBL5999291 0.66 ALDH1A1 (0.40) CYP1A2CYP2C9HIF1ACYP2D6CYP2C19
SCHEMBL6986089 0.65 HSD17B10 (0.42) CYP1A2CYP2C9HIF1ACYP2D6CYP2C19
SCHEMBL8361830 0.63 ALDH1A1 (0.48) CYP1A2CYP2C9HIF1ACYP2D6CYP2C19
SCHEMBL29511774 0.63 PTPN22 (0.39) CYP1A2CYP2C9HIF1ACYP2C19MEN1
SCHEMBL3417362 0.62 SRD5A1 (0.48) CYP2C9HIF1ACYP2D6CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553049-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME LG Chem, Ltd. (KR) 2019-10-16 EP disclosed