Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.75 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 4/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.37 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21476959 | 0.97 | KDM1A (0.76) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21473998 | 0.97 | KDM1A (0.76) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21474135 | 0.97 | KDM1A (0.76) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21476988 | 0.96 | KDM1A (0.77) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21474065 | 0.95 | KDM1A (0.73) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21476972 | 0.95 | KDM1A (0.75) | KDM1ARCOR1LDHBNMT2NMT1 | |
| SCHEMBL21474121 | 0.94 | KDM1A (0.83) | KDM1ARCOR1ESR1ESR2LDHB | |
| SCHEMBL21474132 | 0.94 | KDM1A (0.83) | KDM1ARCOR1ESR1ESR2LDHB | |
| SCHEMBL21474119 | 0.94 | KDM1A (0.83) | KDM1ARCOR1ESR1ESR2LDHB | |
| SCHEMBL21476986 | 0.94 | KDM1A (0.83) | KDM1ARCOR1ESR1ESR2LDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CAMS (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | NPEPPS, MYD88, MRPL21 | KDM1A 2143/4885RCOR1 1398/4885ESR1 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.