Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 2/20 | 0.60 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | HTRA2 | O43464 | 4/20 | 0.51 |
| ▸ | HTRA1 | Q92743 | 4/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384710 | 0.93 | FOLH1 (0.63) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL14932598 | 0.88 | HTRA2 (0.62) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL16295184 | 0.88 | FOLH1 (0.68) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL3289756 | 0.87 | FOLH1 (0.62) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL20997950 | 0.87 | USP2 (0.60) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL15130552 | 0.87 | USP2 (0.62) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL12741017 | 0.87 | FOLH1 (0.61) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL14820144 | 0.85 | FOLH1 (0.59) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL15501046 | 0.84 | FOLH1 (0.59) | FOLH1ALBSLC5A2USP2L3MBTL1 | |
| SCHEMBL13287065 | 0.84 | USP2 (0.60) | FOLH1ALBSLC5A2USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2701699-B1 | INHIBITORS OF HISTONE DEACETYLASE | BROAD INST INC (US) | 2019-10-16 | — | — | EP | disclosed |