SCHEMBL2147907

SCHEMBL2147907

CCc1c(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(CC)c(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(CC)c1Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.58
ALDH1A1 P00352 8/20 0.52
TSHR P16473 3/20 0.52
GAA P10253 3/20 0.52
LMNA P02545 2/20 0.52
MAPK1 P28482 3/20 0.50
HIF1A Q16665 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
BLM P54132 2/20 0.50
ATM Q13315 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
TP53 P04637 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
ALOX15 P16050 2/20 0.50
GMNN O75496 1/20 0.50
GABBR2 O75899 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8395806 1.00 HSPA5 (0.58) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL11413689 0.90 HSPA5 (0.51) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL10752845 0.86 HSPA5 (0.45) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL9063439 0.85 HSPA5 (0.42) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL20699470 0.85 HSPA5 (0.50) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL11074607 0.85 ALDH1A1 (0.55) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL8268168 0.84 HSPA5 (0.62) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL7762204 0.84 HSPA5 (0.62) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL39559 0.83 ALDH1A1 (0.63) HSPA5ALDH1A1TSHRGAALMNA
SCHEMBL11026220 0.83 ALDH1A1 (0.50) HSPA5ALDH1A1TSHRGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4282877-A SHAPED PLASTIC SHEET, PRESSURE SENSITIVE ADHESIVE, DEPILATORY ALLEGHANY PHARMACAL (US) 1981-08-11 US claimed
US-20230225911-A1 ABSORBENT ARTICLE HAVING REAGENTS FOR DETECTING MEDICAL CONDITIONS BABY RX LLC 2023-07-20 US disclosed
US-20220275171-A1 ADDITIVE COMPOSITION ADEKA CORPORATION (JP) 2022-09-01 US disclosed
EP-4006125-A1 ADDITIVE COMPOSITION ADEKA CORPORATION (JP) 2022-06-01 EP disclosed
US-20220064409-A1 ADDITIVE COMPOSITION, FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2022-03-03 US disclosed
CN-113966359-A Additive composition 株式会社艾迪科 2022-01-21 CN disclosed
EP-3835367-A1 ADDITIVE COMPOSITION, FLAME-RETARDANT SYNTHETIC RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2021-06-16 EP disclosed
EP-3444300-B1 FLAME-RETARDANT POLYOLEFIN-BASED RESIN COMPOSITION ADEKA CORP (JP) 2020-11-18 EP disclosed
EP-3444300-A1 FLAME-RETARDANT POLYOLEFIN-BASED RESIN COMPOSITION Adeka Corporation (JP) 2019-02-20 EP disclosed
US-20190040245-A1 FLAME-RETARDANT POLYOLEFIN-BASED RESIN COMPOSITION ADEKA CORPORATION (JP) 2019-02-07 US disclosed
US-20060211794-A1 Long term dimensional stability of pigmented polymer articles CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-21 US disclosed
US-20010036689-A1 Low dielectric constant insulating film resin composition, method of forming low dielectric constant insulating film, and method of producing semiconductor device MUROYAMA MASAKAZU (JP) 2001-11-01 US disclosed
US-5973056-A BLEND OF EPOXY MODIFIED BLOCK COPOLYMER, HYDROCARBON WAX,TACKIFIER RESIN AND ANTIOXIDANT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-10-26 US disclosed
EP-0882775-A1 HOT-MELT ADHESIVE COMPOSITION WITH EXCELLENT HEAT AND COLD RESISTANCE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-09 EP disclosed
EP-0510545-B1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM SPA (IT) 1996-10-02 EP disclosed
EP-0406864-B1 Polyolefin resin composition MITSUI PETROCHEMICAL IND (JP) 1994-03-16 EP disclosed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP disclosed
US-5143979-A Hydrogenated polymer formed by ring-opening polymerization of a norbornene-type polymer NIPPON ZEON CO., LTD (JP) 1992-09-01 US disclosed
EP-0406864-A1 Polyolefin resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
US-4282877-A SHAPED PLASTIC SHEET, PRESSURE SENSITIVE ADHESIVE, DEPILATORY ALLEGHANY PHARMACAL (US) 1981-08-11 US disclosed