Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 3/20 | 0.48 |
| ▸ | TREH | O43280 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.34 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.34 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,5-Anhydrosorbitol SCHEMBL13974561 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL18859863 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL13478979 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL3922510 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL2280560 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL21082117 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL23026253 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL21312807 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL20714515 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 | |
| 1,5-Anhydrosorbitol SCHEMBL17832931 | 1.00 | LGALS3 (0.48) | LGALS3TREHLMNATHRBLGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199634-A1 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | YALE UNIVERSITY (US) | 2019-10-17 | — | — | WO | disclosed |