Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 10/20 | 0.50 |
| ▸ | HTR2B | P41595 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208695 | 1.00 | KDM1A (0.55) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL7492289 | 0.88 | HTR2C (0.63) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL16761697 | 0.88 | HTR2C (0.63) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL1834561 | 0.88 | HTR2C (0.63) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL9043644 | 0.88 | HTR2C (0.63) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL13832388 | 0.82 | P2RY14 (0.47) | KDM1A | |
| SCHEMBL21480337 | 0.81 | KDM1A (0.55) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL20208616 | 0.81 | KDM1A (0.55) | KDM1AMAOBHTR2CHTR2BHTR2A | |
| SCHEMBL19262111 | 0.76 | HTR2C (0.63) | HTR2CHTR2BHTR2A | |
| SCHEMBL17080568 | 0.76 | HTR2C (0.41) | MAOBHTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | AADAC, AAAS, NISCH | KDM1A 3480/4885MAOB 370/4885HTR2C 1098/4885 |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | AADAC, AAAS, NISCH | KDM1A 3480/4885MAOB 370/4885HTR2C 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.