SCHEMBL20208616

SCHEMBL20208616

BrC[C@H]1CC1c1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.55
MAOB P27338 3/20 0.55
HTR2C P28335 15/20 0.50
HTR2B P41595 8/20 0.50
HTR2A P28223 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21480337 1.00 KDM1A (0.55) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL16388354 0.88 HTR2C (0.63) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL3614739 0.88 HTR2C (0.63) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL3619200 0.88 HTR2C (0.63) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL3614757 0.88 HTR2C (0.63) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL20208695 0.81 KDM1A (0.55) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL21480339 0.81 KDM1A (0.55) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL10696871 0.74 HTR2C (0.68) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL10696867 0.74 HTR2C (0.68) KDM1AMAOBHTR2CHTR2BHTR2A
SCHEMBL24529204 0.72 HTR2C (0.67) KDM1AMAOBHTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018095287-A1 BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF 华东理工大学 2018-05-31 WO disclosed