Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | BCR | P11274 | 1/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22817899 | 0.94 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL20419084 | 0.94 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL22817901 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL20419081 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL20419089 | 0.89 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL22817900 | 0.89 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL21480438 | 0.89 | ABL1 (0.60) | ABL1KCNH2BCRCRBN | |
| SCHEMBL21480509 | 0.87 | ABL1 (0.62) | ABL1KCNH2 | |
| SCHEMBL21477625 | 0.86 | ABL1 (0.65) | ABL1KCNH2BCRCRBN | |
| SCHEMBL21477624 | 0.86 | ABL1 (0.64) | ABL1KCNH2BCRCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553057-A1 | (HETERO)ARYLAMIDE COMPOUND FOR INHIBITING PROTEIN KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-10-16 | — | — | EP | disclosed |