Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22817898 | 0.94 | ABL1 (0.64) | ABL1KCNH2 | |
| SCHEMBL20419091 | 0.94 | ABL1 (0.64) | ABL1KCNH2 | |
| SCHEMBL20419086 | 0.89 | ABL1 (0.78) | ABL1KCNH2 | |
| SCHEMBL20419087 | 0.89 | ABL1 (0.69) | ABL1KCNH2 | |
| SCHEMBL22817902 | 0.89 | ABL1 (0.78) | ABL1KCNH2 | |
| SCHEMBL22817907 | 0.89 | ABL1 (0.69) | ABL1KCNH2 | |
| SCHEMBL21480438 | 0.87 | ABL1 (0.60) | ABL1KCNH2 | |
| SCHEMBL21480436 | 0.87 | ABL1 (0.60) | ABL1KCNH2 | |
| SCHEMBL21477624 | 0.85 | ABL1 (0.64) | ABL1KCNH2 | |
| SCHEMBL22837852 | 0.85 | ABL1 (0.65) | ABL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553057-A1 | (HETERO)ARYLAMIDE COMPOUND FOR INHIBITING PROTEIN KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-10-16 | — | — | EP | disclosed |