Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914379 | 0.96 | SCN1A (0.39) | SCN1ASCN2ASCN3AADH1BADH1C | |
| SCHEMBL14296394 | 0.89 | SCN1A (0.42) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL22047671 | 0.86 | SCN1A (0.34) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL5933549 | 0.84 | HSD17B10 (0.33) | MEN1KMT2AADH1BADH1CADH1A | |
| SCHEMBL23696056 | 0.83 | SCN1A (0.37) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL22906505 | 0.83 | KDM4E (0.40) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL21725671 | 0.83 | KDM4E (0.40) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL25123535 | 0.83 | SCN1A (0.37) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL22794300 | 0.83 | HSD17B10 (0.37) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL23696283 | 0.83 | SCN1A (0.37) | SCN1ASCN2ASCN3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |