Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075871 | 1.00 | KDM4E (0.40) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL22906505 | 1.00 | KDM4E (0.40) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL20324094 | 1.00 | KDM4E (0.40) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL20075965 | 1.00 | KDM4E (0.40) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL14296394 | 0.89 | SCN1A (0.42) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL20076071 | 0.88 | CA2 (0.34) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL9546919 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL17386606 | 0.84 | L3MBTL1 (0.44) | KDM4ERECQLSCN1ASCN2ASCN3A | |
| SCHEMBL27838365 | 0.83 | KDM4E (0.40) | KDM4ERECQLMEN1KMT2AL3MBTL1 | |
| SCHEMBL23696283 | 0.83 | SCN1A (0.37) | KDM4ERECQLSCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162173-A1 | COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-05-26 | — | — | US | disclosed |
| US-20200385369-A1 | NEW BENZIMIDAZOLES DERIVATIVES AS TEC KINASES FAMILY INHIBITORS | GB005 INC (US) | 2020-12-10 | — | — | US | disclosed |
| US-10562893-B2 | Benzimidazoles derivatives as Tec kinases family inhibitors | GB005, INC. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562893-B2 | Benzimidazoles derivatives as Tec kinases family inhibitors | BMX, TEC, BTK | KDM4E 2460/4885RECQL 2148/4885SCN1A 4437/4885 |
| US-20220162173-A1 | COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT | GABBR1, GABBR2, PMP22 | KDM4E 2794/4885RECQL 1081/4885SCN1A 339/4885 |
| US-20200385369-A1 | NEW BENZIMIDAZOLES DERIVATIVES AS TEC KINASES FAMILY INHIBITORS | BMX, TEC, BTK | KDM4E 2440/4885RECQL 2229/4885SCN1A 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.