2-Picolinic Acid

2-Picolinic Acid

SCHEMBL2148120

C=CC=C.O=C(O)c1ccccn1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.80
L3MBTL1 Q9Y468 2/20 0.80
NAPRT Q6XQN6 1/20 0.80
P4HTM Q9NXG6 1/20 0.80
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
KMT2A Q03164 2/20 0.55
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 3/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MAPT P10636 1/20 0.51
PKM P14618 1/20 0.51
GSK3B P49841 1/20 0.48
GPR52 Q9Y2T5 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
ACMSD Q8TDX5 1/20 0.45
PTGS2 P35354 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL27417660 0.90 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL28175513 0.90 LMNA (0.91) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.89 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL29368665 0.89
2-Picolinic Acid SCHEMBL36055 0.89
2-Picolinic Acid SCHEMBL7457912 0.89 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL28737810 0.89 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL28173363 0.88 LMNA (0.87) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5667302 0.87 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL22835776 0.87 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541153-B2 Toner for developing electrostatic image, developer for electrostatic image, toner cartridge, process cartridge, image forming method, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-09-24 US disclosed
US-20110171572-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, DEVELOPER FOR ELECTROSTATIC IMAGE, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-07-14 US disclosed
US-20060115757-A1 Toner for development of electrostatic latent image, electrostatic latent image developer, and method for formation of image FUJI XEROX CO., LTD. (JP) 2006-06-01 US disclosed
US-6582867-B2 A crystalline binder resin and a fatty acid ester or a resin having a contact angle with water that is smaller than that of the crystalline resin; electrography; reproducibility in particle size/distribution; low-temperature fixing; stability FUJI XEROX CO., LTD. (JP) 2003-06-24 US disclosed
US-20020055050-A1 Toner for developing electrostatic latent image, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2002-05-09 US disclosed