Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | GLA | P06280 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457081 | 0.92 | ALDH1A1 (0.39) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457054 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21456975 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457039 | 0.87 | SRC (0.40) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL24862196 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457108 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457050 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457003 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457048 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAHTTATM | |
| SCHEMBL21457062 | 0.81 | IGLV6-57 (0.52) | ALDH1A1KDM4EGLAHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553054-A1 | FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF | Universidade de Évora (PT) | 2019-10-16 | — | — | EP | disclosed |