Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801307 | 0.80 | AOC3 (0.48) | AOC3MAOBMAOASMN1; SMN2LOXL2 | |
| Hydrochloric Acid SCHEMBL11154631 | 0.78 | AOC3 (0.53) | AOC3TAAR1MAOBMAOASIGMAR1 | |
| SCHEMBL13696394 | 0.75 | AOC3 (0.59) | AOC3TAAR1MAOBMAOACYP2A6 | |
| SCHEMBL21288940 | 0.74 | AOC3 (0.42) | AOC3LOXL2 | |
| SCHEMBL28896876 | 0.74 | AOC3 (0.44) | AOC3TAAR1MAOBMAOASMN1; SMN2 | |
| SCHEMBL18601889 | 0.73 | CYP1A2 (0.43) | SMN1; SMN2 | |
| SCHEMBL18602019 | 0.73 | CYP3A4 (0.33) | SMN1; SMN2 | |
| SCHEMBL24773983 | 0.73 | CYP3A4 (0.41) | AOC3SMN1; SMN2 | |
| SCHEMBL6651119 | 0.72 | AOC3 (0.67) | AOC3TAAR1MAOBMAOACYP2A6 | |
| SCHEMBL3273331 | 0.72 | AOC3 (0.75) | AOC3TAAR1MAOBMAOACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2732819-B1 | Compounds that enhance Atoh-1 expression | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 2019-10-16 | — | — | EP | disclosed |