SCHEMBL4801307

SCHEMBL4801307

Nc1ccccc1N(N)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.48
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
CA2 P00918 1/20 0.39
POLB P06746 1/20 0.39
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19445246 0.85 CYP2C19 (0.42) AOC3KDM4EALDH1A1CYP2C19
SCHEMBL21288940 0.85 AOC3 (0.42) AOC3KDM4EALDH1A1TSHRCA2
SCHEMBL17739012 0.82 LOXL2 (0.42) AOC3KDM4EALDH1A1TSHRCA2
SCHEMBL2676900 0.81 KDM4E (0.46) AOC3KDM4EALDH1A1TSHRCA2
SCHEMBL21482006 0.80 AOC3 (0.52) AOC3SMN1; SMN2LOXL2MAOAMAOB
SCHEMBL18617301 0.80 NPC1 (0.34) POLBCYP3A4ALOX15CASP1CASP7
SCHEMBL9669617 0.79 KDM4E (0.44) AOC3KDM4EALDH1A1TSHRCA2
SCHEMBL19848742 0.78 HDAC3 (0.44) AOC3KDM4EALDH1A1TSHRCA2
SCHEMBL19848243 0.78 AOC3 (0.44) AOC3ALDH1A1TSHRCYP3A4ALOX15
SCHEMBL9965483 0.78 AOC3 (0.52) AOC3KDM4EALDH1A1TSHRCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1257522-B1 METHOD FOR PRODUCTION OF DIAMINODIPHENYLMETHANES BAYER MATERIALSCIENCE AG (DE) 2006-01-04 EP claimed
EP-3467930-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-10 EP disclosed
US-7390847-B2 Polymer derivatives for the treatment of metals BASF SE (DE) 2008-06-24 US disclosed
WO-2006029823-A2 METHOD FOR THE TREATMENT OF METALLIC SURFACES USING FORMULATIONS BASED ON METHANESULFONIC ACID HAVING A LOW WATER CONTENT BASF AKTIENGESELLSCHAFT (DE) 2006-03-23 WO disclosed
US-20050121114-A1 Polymer derivatives for the treatment of metals BASF AKTIENGESELLSCHAFT (DE) 2005-06-09 US disclosed
EP-1470198-A2 POLYMER DERIVATIVES FOR THE TREATMENT OF METALS BASF AKTIENGESELLSCHAFT (DE) 2004-10-27 EP disclosed
WO-2003056061-A2 POLYMER DERIVATIVES FOR THE TREATMENT OF METALS BASF AKTIENGESELLSCHAFT (DE) 2003-07-10 WO disclosed
US-4965331-A DIPROPARGYL ETHER OF BISPHENOL A AND BIS-OR POLY-MALEIMIDE SHELL OIL COMPANY (US) 1990-10-23 US disclosed