⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480663 | 0.84 | — | — | |
| SCHEMBL8854824 | 0.84 | CHRM1 (0.44) | — | |
| SCHEMBL11240727 | 0.82 | CHRM1 (0.44) | — | |
| SCHEMBL9787814 | 0.81 | CHRM1 (0.42) | — | |
| SCHEMBL7942491 | 0.78 | CHRM1 (0.48) | — | |
| SCHEMBL22790740 | 0.78 | CHRM1 (0.34) | — | |
| SCHEMBL1712733 | 0.77 | — | — | |
| Acetic Acid SCHEMBL8495226 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL1712734 | 0.77 | — | — | |
| SCHEMBL498121 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10857105-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | MordernaTX, Inc. (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190314292-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2019-10-17 | — | — | US | disclosed |