SCHEMBL2148222

SCHEMBL2148222

C=C(C)CC(CCC(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 15/20 0.65
GRM3 Q14832 2/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.47
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2159796 0.88 FOLH1 (0.50) FOLH1CYP1A2
SCHEMBL13753333 0.83 FOLH1 (0.71) FOLH1GRM3NAALAD2CYP1A2
SCHEMBL31198158 0.82 TDP1 (0.42) FOLH1
SCHEMBL7541278 0.81 CHRM1 (0.62) FOLH1
SCHEMBL14574037 0.81 CHRM1 (0.62) FOLH1
SCHEMBL9514344 0.80 FOLH1 (0.48) FOLH1
SCHEMBL9725558 0.80 FOLH1 (0.48) FOLH1
SCHEMBL28640 0.80 FOLH1 (1.00) FOLH1GRM3NAALAD2
SCHEMBL9188814 0.79 FOLH1 (0.65) FOLH1GRM3NAALAD2
SCHEMBL31756901 0.78 CHRM1 (0.50) FOLH1GRM3NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP claimed
EP-1773903-B1 SUPRAMOLECULAR IONOMERS SUPRAPOLIX BV (NL) 2017-08-09 EP disclosed
US-9089500-B2 Cosmetic treatment processes and kit L'OREAL (FR) 2015-07-28 US disclosed
US-20140155352-A1 COSMETIC TREATMENT PROCESSES AND KIT L'OREAL (FR) 2014-06-05 US disclosed
EP-2729118-A2 COSMETIC TREATMENT PROCESSES AND KIT L'OREAL (FR) 2014-05-14 EP disclosed
WO-2013004982-A2 COSMETIC TREATMENT PROCESSES AND KIT L'OREAL (FR) 2013-01-10 WO disclosed
US-8268952-B2 Supramolecular ionomers SUPRAPOLIX B.V. (NL) 2012-09-18 US disclosed
WO-2011083243-A1 COSMETIC TREATMENT METHODS AND KIT L'OREAL (FR) 2011-07-14 WO disclosed
US-20090111930-A1 Supramolecular Ionomers SUPRAPOLIX B. V. 2009-04-30 US disclosed
EP-1797868-A1 Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment L'Oréal (FR) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155352-A1 COSMETIC TREATMENT PROCESSES AND KIT KIT, KRT18, MKI67 FOLH1 1115/4885GRM3 4861/4885NAALAD2 2768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.