SCHEMBL2159796

SCHEMBL2159796

C=C(C)CC(CCCC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 12/20 0.50
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP1A2 P05177 1/20 0.38
ENPEP Q07075 2/20 0.37
GSTK1 Q9Y2Q3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148222 0.88 FOLH1 (0.65) FOLH1CYP1A2
SCHEMBL17200670 0.82 CA2 (0.61) FOLH1CA2MAPK1
SCHEMBL2483229 0.81 FOLH1 (0.74) FOLH1ENPEP
SCHEMBL9292494 0.79 GRIK1 (0.54) CA2MAPK1
SCHEMBL2304730 0.79 GRIK1 (0.54) CA2MAPK1
SCHEMBL31198158 0.79 TDP1 (0.42) FOLH1CA2MAPK1
SCHEMBL8844774 0.78 FOLH1 (0.47) FOLH1ENPEPGSTK1
SCHEMBL22500685 0.78 GABRP (0.39) CYP1A2ENPEPGSTK1
SCHEMBL7541278 0.78 CHRM1 (0.62) FOLH1CA2MAPK1
SCHEMBL14574037 0.78 CHRM1 (0.62) FOLH1CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4051003-A DIELECTRIC COATINGS INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1977-09-27 US claimed
US-4031167-A COATINGS INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1977-06-21 US claimed
US-10377847-B2 Strong reversible hydrogels SUPRAPOLIX B.V. (NL) 2019-08-13 US disclosed
EP-1773903-B1 SUPRAMOLECULAR IONOMERS SUPRAPOLIX BV (NL) 2017-08-09 EP disclosed
EP-2343342-B1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX BV (NL) 2015-09-16 EP disclosed
US-9006364-B2 Supramolecular polymers from low-melting, easily processable building blocks SUPRAPOLIX B.V. (NL) 2015-04-14 US disclosed
US-20140142256-A1 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2014-05-22 US disclosed
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. (NL) 2014-05-08 US disclosed
US-8628789-B2 Strong reversible hydrogels SUPRAPOLIX, B.V. (NL) 2014-01-14 US disclosed
US-8268952-B2 Supramolecular ionomers SUPRAPOLIX B.V. (NL) 2012-09-18 US disclosed
EP-2087027-B1 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX BV (NL) 2011-10-05 EP disclosed
US-20090111930-A1 Supramolecular Ionomers SUPRAPOLIX B. V. 2009-04-30 US disclosed
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS SUPRAPOLIX B.V. 2008-10-23 US disclosed
EP-1972661-A1 Strong reversible hydrogels SupraPolix B.V. (NL) 2008-09-24 EP disclosed
WO-2008063057-A2 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2008-05-29 WO disclosed
EP-1773903-A1 SUPRAMOLECULAR IONOMERS SupraPolix B.V. (NL) 2007-04-18 EP disclosed
WO-2006006855-A1 SUPRAMOLECULAR IONOMERS SUPRAPOLIX B.V. (NL) 2006-01-19 WO disclosed
US-4078114-A CROSSLINKING FLUOROPOLYMERS INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1978-03-07 US disclosed
US-4051003-A DIELECTRIC COATINGS INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1977-09-27 US disclosed
US-4031167-A COATINGS INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10377847-B2 Strong reversible hydrogels HSPA4L, H1-4, CD44 FOLH1 4292/4885CA2 4259/4885MAPK1 2725/4885
US-20080260795-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 FOLH1 4292/4885CA2 4259/4885MAPK1 2725/4885
US-20140128482-A1 STRONG REVERSIBLE HYDROGELS HSPA4L, H1-4, CD44 FOLH1 4292/4885CA2 4259/4885MAPK1 2725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.