SCHEMBL21482269 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CARM1	Q86X55	4/20	0.52

▸	HDAC2	Q92769	1/20	0.44

▸	ATR	Q13535	13/20	0.42

▸	CHEK1	O14757	1/20	0.39

▸	PDCD1	Q15116	1/20	0.39

▸	CD274	Q9NZQ7	1/20	0.39

▸	ROCK2	O75116	1/20	0.39

▸	ROCK1	Q13464	1/20	0.39

▸	HPGD	P15428	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21462110	0.92	CARM1 (0.58)	CARM1ATRCHEK1PDCD1CD274
SCHEMBL21462145	0.86	CARM1 (0.55)	CARM1HDAC2ATRCHEK1PDCD1
SCHEMBL21462156	0.86	ATR (0.43)	ATRCHEK1PDCD1CD274ROCK2
SCHEMBL21462268	0.84	ATR (0.61)	ATRCHEK1PDCD1CD274
SCHEMBL21462267	0.84	ATR (0.61)	ATRCHEK1PDCD1CD274
SCHEMBL21482358	0.83	CARM1 (0.55)	CARM1HDAC2ROCK1
SCHEMBL21482280	0.80	CARM1 (0.62)	CARM1HDAC2ATR
SCHEMBL21482292	0.75	CARM1 (0.72)	CARM1HDAC2
SCHEMBL21482368	0.74	PIK3CA (0.53)	CARM1ATR
SCHEMBL1719623	0.71	NUDT1 (0.61)	CARM1ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019196720-A1	ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF	中国科学院上海药物研究所	2019-10-17	—	—	WO	disclosed