Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648927 | 0.87 | TLR4 (0.34) | TLR4 | |
| SCHEMBL9648917 | 0.87 | TLR4 (0.34) | TLR4 | |
| SCHEMBL20664421 | 0.82 | TSHR (0.39) | TLR4ALDH1A1MAPK1 | |
| SCHEMBL9649190 | 0.80 | TLR4 (0.33) | TLR4 | |
| SCHEMBL9649194 | 0.80 | TLR4 (0.33) | TLR4 | |
| SCHEMBL6750485 | 0.78 | TLR4 (0.41) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9442488 | 0.78 | TLR4 (0.41) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9650117 | 0.77 | CYP1A2 (0.34) | TLR4LMNAMAPK1 | |
| SCHEMBL9650124 | 0.77 | CYP1A2 (0.34) | TLR4LMNAMAPK1 | |
| SCHEMBL13361196 | 0.77 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-9255223-B2 | Polymerizable compounds and liquid crystal media | MERCK PATENT GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| US-9255223-B2 | Polymerizable compounds and liquid crystal media | MERCK PATENT GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| EP-2931838-A1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014094959-A1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014094959-A1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| US-20120298916-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-29 | — | — | US | disclosed |
| US-20120298916-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-29 | — | — | US | disclosed |
| US-20120298916-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-29 | — | — | US | disclosed |
| WO-2011088882-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011088882-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | LASP1, VCL, NEFM | TLR4 2799/4885CYP2C9 4189/4885ALDH1A1 4616/4885 |
| US-20120298916-A1 | POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA | RCC1, CCNB2, CCNB1 | TLR4 4114/4885CYP2C9 2076/4885ALDH1A1 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.