Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 7/20 | 0.48 |
| ▸ | PRKCI | P41743 | 5/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15645614 | 0.78 | NUDT1 (0.55) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL15645224 | 0.78 | NUDT1 (0.51) | NUDT1PRKCIAXLAURKBJAK2 | |
| Hydrochloric Acid SCHEMBL28111964 | 0.77 | NUDT1 (0.50) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL29702872 | 0.73 | NUDT1 (0.60) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL1456822 | 0.73 | NUDT1 (0.60) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL18602380 | 0.72 | NUDT1 (0.49) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL12653267 | 0.72 | NUDT1 (0.49) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL12618980 | 0.72 | NUDT1 (0.49) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL3254384 | 0.71 | NUDT1 (0.63) | NUDT1PRKCIAXLAURKBJAK2 | |
| SCHEMBL2606616 | 0.71 | NUDT1 (0.66) | NUDT1PRKCIAXLAURKBJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196720-A1 | ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2019-10-17 | — | — | WO | disclosed |