⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564 | 0.97 | — | — | |
| SCHEMBL24409361 | 0.97 | — | — | |
| Bromide SCHEMBL3825715 | 0.94 | — | — | |
| Iodide SCHEMBL3654797 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL2706385 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL3339719 | 0.94 | CHRNA7 (0.35) | — | |
| Bromide SCHEMBL29585852 | 0.92 | CHRNA7 (0.33) | — | |
| SCHEMBL27729 | 0.91 | — | — | |
| SCHEMBL3399160 | 0.89 | — | — | |
| SCHEMBL875158 | 0.88 | CHRNA7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12478620-B2 | Cyano-substituted cyclic hydrazine derivative and application thereof | E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD (CN) | 2025-11-25 | — | — | US | disclosed |
| US-20220339146-A1 | CYANO-SUBSTITUTED CYCLIC HYDRAZINE DERIVATIVE AND APPLICATION THEREOF | E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD (CN) | 2022-10-27 | — | — | US | disclosed |
| EP-4032888-A1 | CYANO-SUBSTITUTED CYCLIC HYDRAZINE DERIVATIVE AND APPLICATION THEREOF | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd (CN) | 2022-07-27 | — | — | EP | disclosed |
| US-8697691-B2 | Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate analogs as selective M1 agonists and methods of making and using same | VANDERBILT UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| WO-2011087812-A1 | ALKYL 3-((2-AMIDOETHYL)AMINO)-8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXYLATE ANALOGS AS SELECTIVE M1 AGONISTS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY (US) | 2011-07-21 | — | — | WO | disclosed |
| US-20110172227-A1 | ALKYL 3-((2-AMIDOETHYL)AMINO)-8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXYLATE ANALOGS AS SELECTIVE M1 AGONISTS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY | 2011-07-14 | — | — | US | disclosed |