Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729 | 0.97 | — | — | |
| SCHEMBL24409361 | 0.91 | — | — | |
| SCHEMBL7593004 | 0.91 | CYP2D6 (0.32) | CHRNA7 | |
| SCHEMBL28564 | 0.91 | — | — | |
| SCHEMBL2148332 | 0.88 | — | — | |
| SCHEMBL4175185 | 0.88 | CHRM5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3339719 | 0.88 | CHRNA7 (0.35) | CHRNA7 | |
| Iodide SCHEMBL3654797 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL2706385 | 0.88 | — | — | |
| Bromide SCHEMBL3825715 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619205-A1 | MONOHYDRATE OF AN AZAADAMANTANE DERIVATIVE | AbbVie Inc. (US) | 2013-07-31 | — | — | EP | claimed |
| WO-2012040404-A1 | MONOHYDRATE OF AN AZAADAMANTANE DERIVATIVE | ABBOTT LABORATORIES (US) | 2012-03-29 | — | — | WO | claimed |
| EP-2619205-A1 | MONOHYDRATE OF AN AZAADAMANTANE DERIVATIVE | AbbVie Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040404-A1 | MONOHYDRATE OF AN AZAADAMANTANE DERIVATIVE | ABBOTT LABORATORIES (US) | 2012-03-29 | — | — | WO | disclosed |
| EP-2139891-A1 | 4-SUBSTITUTED AZAADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2010-01-06 | — | — | EP | disclosed |
| EP-2069346-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008118743-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008118745-A1 | 4-SUBSTITUTED AZAADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | WO | disclosed |
| EP-1068208-A1 | AZATRICYCLO[3.3.1.1] DECANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | R.J. REYNOLDS TOBACCO COMPANY (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051602-A1 | AZATRICYCLO[3.3.1.1] DECANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | R.J. REYNOLDS TOBACCO COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |