Urethane

Urethane

SCHEMBL21483479

C=C(C)C(=O)OC(C)C.CCOC(N)=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.54
TSHR P16473 6/20 0.44
THRB P10828 1/20 0.42
ALDH1A1 P00352 7/20 0.35
LMNA P02545 3/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
GLO1 Q04760 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4858633 0.88 ALOX15 (0.52) ALOX15TSHRTHRBALDH1A1LMNA
SCHEMBL11295643 0.87 TSHR (0.53) ALOX15TSHRTHRBALDH1A1LMNA
Urethane SCHEMBL8854346 0.83 ALOX15 (0.50) ALOX15TSHRTHRBALDH1A1LMNA
Urethane SCHEMBL2787852 0.83 ALOX15 (0.65) ALOX15TSHRTHRBALDH1A1LMNA
Urethane SCHEMBL728774 0.82 ALOX15 (0.79) ALOX15TSHRTHRBALDH1A1LMNA
Urethane SCHEMBL21483475 0.81 ALOX15 (0.44) ALOX15TSHRTHRBALDH1A1CHRNB2
Urethane SCHEMBL28935573 0.81 ALOX15 (0.62) ALOX15TSHRALDH1A1LMNAHSD17B10
Urethane SCHEMBL9720810 0.81 TSHR (0.72) ALOX15TSHRTHRBALDH1A1LMNA
Urethane SCHEMBL27170951 0.80 ALOX15 (0.75) ALOX15TSHRTHRBALDH1A1LMNA
SCHEMBL21772350 0.80 TSHR (0.52) TSHRTHRBALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556817-B1 FUNCTIONALIZED POLYMER COMPOSITIONS FOR LOW VOC COALESCENCE OF WATER BASED EMULSIONS UNIV AKRON (US) 2021-12-15 EP disclosed
US-11084952-B2 Functionalized polymer compositions for low VOC coalescence of water based emulsions SWIMC, LLC (US) 2021-08-10 US disclosed
US-20190322890-A1 FUNCTIONALIZED POLYMER COMPOSITIONS FOR LOW VOC COALESCENCE OF WATER BASED EMULSIONS SWIMC LLC 2019-10-24 US disclosed
EP-3556817-A1 FUNCTIONALIZED POLYMER COMPOSITIONS FOR LOW VOC COALESCENCE OF WATER BASED EMULSIONS The University of Akron (US) 2019-10-23 EP disclosed