SCHEMBL2148358

SCHEMBL2148358

C=C(C=O)CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL31395153 0.87 FFAR3 (0.35)
SCHEMBL1135773 0.78
SCHEMBL12162728 0.78
SCHEMBL5139910 0.72
SCHEMBL10356912 0.71
SCHEMBL18531168 0.69
SCHEMBL13265438 0.69 ALDH1A1 (0.32)
SCHEMBL9110174 0.69
SCHEMBL10000892 0.69
SCHEMBL1834565 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976106-B (E) Synthesis method of (E) -2-methylene-1, 4-butanedione compounds 河南师范大学 2021-02-19 CN claimed
CN-108976106-B (E) Synthesis method of (E) -2-methylene-1, 4-butanedione compounds 河南师范大学 2021-02-19 CN disclosed
CN-108976106-B (E) Synthesis method of (E) -2-methylene-1, 4-butanedione compounds 河南师范大学 2021-02-19 CN disclosed
CN-108976106-B (E) Synthesis method of (E) -2-methylene-1, 4-butanedione compounds 河南师范大学 2021-02-19 CN disclosed
US-20150232595-A1 RESIN MIXTURE BASED ON VINYL ESTER RESIN, REACTIVE RESIN MORTAR COMPRISING SAME AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2015-08-20 US disclosed
US-8586245-B2 Battery SONY CORPORATION (JP) 2013-11-19 US disclosed
US-20110177399-A1 BATTERY SONY CORPORATION (JP) 2011-07-21 US disclosed
US-RE41539-E1 Breathable composite sheet structure and absorbent articles utilizing same THE PROCTER & GAMBLE COMPANY (US) 2010-08-17 US disclosed
US-7365091-B2 Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX ENOBIA PHARMA (CA) 2008-04-29 US disclosed
US-20080038218-A1 Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent L'OREAL S.A. (FR) 2008-02-14 US disclosed
US-20020094742-A1 Method for protecting surfaces of packed articles E. I. DU PONT DE NEMOURS AND COMPANY 2002-07-18 US disclosed
US-20020019187-A1 BREATHABLE COMPOSITE SHEET STRUCTURE AND ABSORBENT ARTICLES UTILIZING SAME PROCTER AND GAMBLE COMPANY, THE 2002-02-14 US disclosed
EP-0906192-B1 BREATHABLE COMPOSITE SHEET STRUCTURE AND ABSORBENT ARTICLES UTILIZING SAME DU PONT (US) 2001-10-31 EP disclosed
EP-0608361-B1 ROOT CANAL FILLING MATERIAL AND ADHESIVE COMPOSITION ESSENTIAL DENTAL SYSTEMS INC (US) 2001-03-14 EP disclosed
EP-0906192-A1 BREATHABLE COMPOSITE SHEET STRUCTURE AND ABSORBENT ARTICLES UTILIZING SAME E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-07 EP disclosed
WO-1997045259-A1 BREATHABLE COMPOSITE SHEET STRUCTURE AND ABSORBENT ARTICLES UTILIZING SAME E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-04 WO disclosed
EP-0608361-A1 ROOT CANAL FILLING MATERIAL AND ADHESIVE COMPOSITION ESSENTIAL DENTAL SYSTEMS, INC. (US) 1994-08-03 EP disclosed
US-5263861-A Root canal filling material and adhesive composition ESSENTIAL DENTAL SYSTEMS, INC. (US) 1993-11-23 US disclosed
US-5236362-A Inserting thermoset resin in root canal and adhesive material suitable for maintaining polymer in root canal ESSENTIAL DENTAL SYSTEMS, INC. (US) 1993-08-17 US disclosed
WO-1993010176-A1 ROOT CANAL FILLING MATERIAL AND ADHESIVE COMPOSITION ESSENTIAL DENTAL SYSTEMS, INC. (US) 1993-05-27 WO disclosed