Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148405 | 1.00 | TOP2A (0.41) | TOP2AHDAC1 | |
| SCHEMBL15061815 | 0.91 | TOP2A (0.43) | TOP2AHDAC1 | |
| SCHEMBL18844509 | 0.91 | TOP2A (0.43) | TOP2AHDAC1 | |
| SCHEMBL20953734 | 0.91 | TOP2A (0.43) | TOP2AHDAC1 | |
| SCHEMBL20974279 | 0.91 | TOP2A (0.43) | TOP2AHDAC1 | |
| SCHEMBL18855391 | 0.89 | TOP2A (0.42) | TOP2AHDAC1 | |
| SCHEMBL18844492 | 0.89 | TOP2A (0.42) | TOP2AHDAC1 | |
| SCHEMBL2128874 | 0.89 | TOP2A (0.42) | TOP2AHDAC1 | |
| SCHEMBL2128870 | 0.89 | TOP2A (0.42) | TOP2AHDAC1 | |
| SCHEMBL12047224 | 0.89 | TOP2A (0.42) | TOP2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255292-B2 | Synthesis of four-color 3′-O-allyl modified photocleavable fluorescent nucleotides and related methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-02-09 | — | — | US | disclosed |
| US-20120156680-A1 | SYNTHESIS OF FOUR-COLOR 3'-O-ALLYL MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2012-06-21 | — | — | US | disclosed |
| US-7982029-B2 | Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-07-19 | — | — | US | disclosed |
| US-20100041029-A1 | SYNTHESIS OF FOUR COLOR 3'O-ALLYL, MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-02-18 | — | — | US | disclosed |