SCHEMBL21484978

SCHEMBL21484978

CCCCCCCCCCCCc1ccsc1-c1sc(-c2ccc(-c3cccs3)s2)cc1CCCCCCCCCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.39
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 4/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
GAA P10253 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36
ADK P55263 1/20 0.35
LTA4H P09960 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TP53 P04637 2/20 0.33
POLB P06746 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 2/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15549170 1.00 DPP4 (0.39) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL19616027 0.94 ADK (0.35) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL6365054 0.94 DPP4 (0.43) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL12264399 0.90 ADK (0.40) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL6034454 0.86 ADK (0.37) ALDH1A1KDM4ENPC1RAB9AGAA
SCHEMBL85810 0.86 TYR (0.35) MAPTMEN1KMT2ATP53LIPG
SCHEMBL18090329 0.86 TYR (0.35) MAPTMEN1KMT2ATP53LIPG
SCHEMBL10819415 0.86 TYR (0.35) MAPTMEN1KMT2ATP53LIPG
SCHEMBL10164725 0.86 TYR (0.35) MAPTMEN1KMT2ATP53LIPG
SCHEMBL85733 0.86 TYR (0.35) MAPTMEN1KMT2ATP53LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555929-A1 POLAR ELASTOMER MICROSTRUCTURES AND METHODS FOR FABRICATING SAME Corning Incorporated (US) 2019-10-23 EP disclosed