Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16782218 | 0.97 | CYP19A1 (0.39) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| Hypochlorous Acid SCHEMBL21486125 | 0.96 | CYP19A1 (0.37) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| Hydrochloric Acid SCHEMBL15228343 | 0.96 | CYP19A1 (0.39) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| SCHEMBL15230345 | 0.94 | CYP19A1 (0.37) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| Hydrochloric Acid SCHEMBL15230492 | 0.93 | CYP19A1 (0.36) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| Hypochlorous Acid SCHEMBL21486083 | 0.88 | CYP19A1 (0.36) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| Hypochlorous Acid SCHEMBL21486023 | 0.88 | CYP19A1 (0.36) | CYP19A1SUV39H2DGAT1TP53NPC1 | |
| SCHEMBL15230883 | 0.87 | NPC1 (0.46) | CYP19A1SUV39H2TP53NPC1RAB9A | |
| SCHEMBL15228368 | 0.87 | CYP19A1 (0.40) | CYP19A1DGAT1TP53NPC1RAB9A | |
| SCHEMBL15230271 | 0.85 | CYP19A1 (0.36) | CYP19A1SUV39H2TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819519-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | claimed |