Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | CASP2 | P42575 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6575430 | 0.98 | BLM (0.47) | BLMDRD3CA12CA2CA4 | |
| Water SCHEMBL5319737 | 0.98 | BLM (0.47) | BLMDRD3CA12CA2CA4 | |
| Water SCHEMBL8576389 | 0.98 | BLM (0.47) | BLMDRD3CA12CA2CA4 | |
| SCHEMBL9172734 | 0.85 | DRD3 (0.52) | BLMDRD3CA12CA2CA4 | |
| SCHEMBL29021959 | 0.82 | DRD3 (0.46) | BLMDRD3CA12CA2CA4 | |
| SCHEMBL2148646 | 0.80 | SAT1 (0.62) | CA12CA2CA9CYP1A2MEN1 | |
| SCHEMBL4388966 | 0.80 | SAT1 (0.45) | CA12CA2CA9CA1SAT1 | |
| SCHEMBL8722018 | 0.77 | CA12 (0.46) | BLMDRD3CA12CA2CA4 | |
| SCHEMBL14782501 | 0.76 | ANPEP (0.44) | BLMDRD3CA12CA2CA4 | |
| SCHEMBL5247222 | 0.76 | LPAR3 (0.42) | BLMCA12CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200360406-A1 | SELECTIVE ACCRETION OF CYTOPROTECTANT IN RADIATION-SENSITIVE TISSUES AND USES THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2020-11-19 | — | — | US | claimed |
| US-6573253-B2 | Protecting against or treating toxicities associated with ionizing radiation by subcutaneously administering compounds such as S-3-(3-methylaminopropylamino)propyl dihydrogen phosphorothioate prior to exposure | MEDIMMUNE ONCOLOGY INC. | 2003-06-03 | — | — | US | claimed |
| US-5906984-A | Methods of using aminothiols to promote hematopoietic progenitor cell growth | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1999-05-25 | — | — | US | claimed |
| US-5804571-A | ADMINISTERING AN S-OMEGA(OMEGA-AMINOALKYLAMINO)ALKYL DIHYDROGEN PHOSPHOROTHIOATE | U.S. BIOSCIENCE (US) | 1998-09-08 | — | — | US | claimed |
| WO-2024211590-A1 | PHARMACEUTICALLY ACTIVE COMPOSITIONS AND USES THEREOF | XERIENT PHARMA LTD. (IL) | 2024-10-10 | — | — | WO | disclosed |
| US-11478489-B2 | Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof | WILLIAM MARSH RICE UNIVERSITY (US) | 2022-10-25 | — | — | US | disclosed |
| US-20200360406-A1 | SELECTIVE ACCRETION OF CYTOPROTECTANT IN RADIATION-SENSITIVE TISSUES AND USES THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2020-11-19 | — | — | US | disclosed |
| EP-3713534-A1 | SELECTIVE ACCRETION OF CYTOPROTECTANT IN RADIATION-SENSITIVE TISSUES AND USES THEREOF | William Marsh Rice University (US) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019103983-A1 | SELECTIVE ACCRETION OF CYTOPROTECTANT IN RADIATION-SENSITIVE TISSUES AND USES THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |
| EP-2714715-B1 | PHARMACEUTICAL COMPOSITIONS | SEECURE TAIWAN CO LTD (TW) | 2019-01-23 | — | — | EP | disclosed |
| US-8648042-B2 | Pharmaceutical compositions | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2014-02-11 | — | — | US | disclosed |
| US-20130090312-A1 | METHODS OF USE RELATED TO XEROSTOMIA | MEDIMMUNE LLC (US) | 2013-04-11 | — | — | US | disclosed |
| EP-0409845-A4 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | — | 1991-07-03 | — | — | EP | disclosed |
| EP-0409845-A4 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | — | 1991-07-03 | — | — | EP | disclosed |
| US-5017693-A | Methods for introducing a sulfhydryl amino or hydroxyl groups to a compound | NEORX CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0409845-A1 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | U.S. BIOSCIENCE (US) | 1991-01-30 | — | — | EP | disclosed |
| EP-0409845-A1 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | U.S. BIOSCIENCE (US) | 1991-01-30 | — | — | EP | disclosed |
| WO-1990014007-A1 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | U.S. BIOSCIENCE (US) | 1990-11-29 | — | — | WO | disclosed |
| WO-1989007942-A1 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | U.S. BIOSCIENCE (US) | 1989-09-08 | — | — | WO | disclosed |
| WO-1989007942-A1 | METHOD FOR PROTECTION FROM CHEMOTHERAPEUTIC SIDE EFFECTS | U.S. BIOSCIENCE (US) | 1989-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478489-B2 | Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof | HSPE1, TXNRD2, TXN2 | BLM 789/4885DRD3 4644/4885CA12 2244/4885 |
| US-20200360406-A1 | SELECTIVE ACCRETION OF CYTOPROTECTANT IN RADIATION-SENSITIVE TISSUES AND USES THEREOF | HSPE1, TXNRD2, TXN2 | BLM 789/4885DRD3 4644/4885CA12 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.